Publications

Cho group members in bold, *Corresponding author

Yeast biopanning against site-specific phosphorylations in tau
Protein Engineering Design & Selection, 2023
Arbaciauskaite, M., Pirhanov, A., Ammermann, E., Lei, Y., Cho, Y.K.*
DOI:10.1093/protein/gzad005

Depth-multiplexed ptychographic microscopy for high-throughput imaging of stacked bio-specimens on a chip
Biosensors and Bioelectronics, 2023
Chengfei Guo, Shaowei Jiang, Liming Yang, Pengming Song, Azady Pirhanov, Ruihai Wang, Tianbo Wang, Xiaopeng Shao, Qian Wu, Yong Ku Cho, Guoan Zheng*
DOI:10.1016/j.bios.2022.115049

Targeted degradation of microtubule-associated protein tau using an engineered nanobody-E3 ubiquitin ligase adapter fusion
bioRxiv, 2022
Wang, S., Jiang, S., Zheng, G., Cho, Y.K.*
DOI:bioRxiv

Degradation-driven protein level oscillations in the yeast Saccharomyces cerevisiae
Biosystems, 2022
Mahrou, B.*, Pirhanov, A., Alijanvand, M., Cho, Y.K.*, Shin, Y.-J.
DOI:10.1016/j.biosystems.2022.104717

High specificity antibodies and detection methods for quantifying phosphorylated tau from clinical samples
Antibody Therapeutics, 2021
Arbaciauskaite, M., Lei, Y., Cho, Y.K.*
DOI:10.1093/abt/tbab004

Optogenetics in Sinorhizobium meliloti enables spatial control of exopolysaccharide production and biofilm structure
ACS Synthetic Biology, 2021
Pirhanov, A., Bridges, C.M., Goodwin, R.A., Guo, Y-S., Furrer, J., Shor, L.M., Gage, D.J., Cho, Y.K.*
DOI:10.1021/acssynbio.0c00498

Yeast surface display of full-length human microtubule-associated protein tau
Biotechnology Progress, 2020
Wang, S., Cho, Y.K.*
DOI:10.1002/btpr.2920
–On the cover

High specificity of widely used phospho-tau antibodies validated using a quantitative whole-cell based assay
Journal of Neurochemistry, 2020
Li, D., Cho, Y.K.*
DOI:10.1111/jnc.14830
–Selected as cover image

A yeast display immunoprecipitation screen for targeted discovery of antibodies against membrane protein complexes
Protein Engineering Design and Selection, 2019
Lajoie, J., Cho, Y.K., Frost, D., Bremner, S., Li, L., Shusta, E.V.*
DOI:10.1093/protein/gzz035

Multidimensional screening yields channelrhodopsin variants having improved photocurrent and order-of-magnitude reductions in calcium and proton currents
Journal of Biological Chemistry, 2019
Cho, Y.K., Park, D., Yang, A., Chen, F., Chuong, A.S., Klapoetke, N.C., Boyden, E.S.*
DOI:10.1074/jbc.RA118.006996
Author Profile: Yong Ku Cho

Bacterial Extracellular Polymeric Substances Amplify Water Content Variability at the Pore Scale
Frontiers in Environmental Science, 2018
Guo, Y.S., Furrer, J.M., Kadilak, A., Hinestroza, H.F., Gage, D.G., Cho, Y.K., Shor, L.M.*
DOI:10.3389/fenvs.2018.00093

Directed evolution of a picomolar affinity high-specificity antibody targeting phosphorylated tau
Journal of Biological Chemistry, 2018
Li, D., Wang, L., Maziuk, B.F., Yao, X., Wolozin, B., Cho, Y.K.*
DOI:10.1074/jbc.RA118.003557
Selected in Virtual Issue: Antibody Engineering

Yeast display biopanning identifies human antibodies targeting glioblastoma stem-like cells
Scientific Reports, 2017
M Zorniak, PA Clark, BJ Umlauf, YK Cho, EV Shusta*, JS Kuo*
DOI:10.1038/s41598-017-16066-1

Rapid focus map surveying for whole slide imaging with continuous sample motion
Optics Letters, 2017
Liao, J, Jiang Y, Bian Z, Mahrou B, Nambiar A, Magsam AW, Guo K, Wang S, Cho YK, Zheng G*
DOI:10.1364/OL.42.003379

Poreā€scale water dynamics during drying and the impacts of structure and surface wettability
Water Resources Research, 2017
Cruz BC, Furrer JM, Guo YS, Dougherty D, Hinestroza HF, Hernandez JS, Gage DJ, Cho YK, Shor LM*
DOI:10.1002/2016WR019862

Roadmap on neurophotonics
Journal of Optics, 2016
Cho YK*, Zheng G*, Augustine GJ, Hochbaum D, Cohen A, Knopfel T, Pisanello F, Pavone FS, Vellekoop IM, Booth MJ, Hu S, Zhu J, Chen Z, Hoshi Y
DOI:10.1088/2040-8978/18/9/093007

Building Blocks for Bottom-Up Neural Tissue Engineering: Tools for In Vitro Assembly and Interrogation of Neural Circuits (book chapter)
Neural Engineering, 2016
Knowlton S, Li D, Ersoy F, Cho YK*, Tasoglu S*
DOI:10.1007/978-3-319-31433-4_4

Novel green and red autofluorescent protein nanoparticles for cell imaging and in vivo biodegradation imaging and modeling
RSC Advances, 2016
Ma X, Hargrove D, Dong Q, Song D, Chen J, Wang S, Lu X, Cho YK, Fan TH*, Lei Y*
DOI:10.1039/C6RA06783B

An Optimized Calcium-Phosphate Transfection Method for Characterizing Genetically Encoded Tools in Primary Neurons (book chapter)
Methods in Molecular Biology, 2016
Wang S, Cho YK*
DOI:10.1007/978-1-4939-3512-3_16

Optogenetics: Basic Concepts and Their Development (book chapter)
Methods in Molecular Biology, 2016
Cho YK*, Li D
DOI:10.1007/978-1-4939-3512-3_1

Utilizing stem cells for three-dimensional neural tissue engineering
Biomaterials Science, 2016
Knowlton S, Cho YK, Li XJ, Khademhosseini A, Tasoglu S*
DOI:10.1039/C5BM00324E

Genetically Encoded Tools: Bridging the Gap between Neuronal Identity and Function
ACS Chemical Neuroscience, 2015
Cho YK*
DOI:10.1021/acschemneuro.5b00008

Natural photoreceptors and their application to synthetic biology
Trends in Biotechnology, 2015
Schmidt D*, Cho YK*
DOI:10.1016/j.tibtech.2014.10.007

 

Prior to UConn

Engineered microbial rhodopsins for all optical electrophysiology in mammalian neurons
Nature Methods, 2014
Hochbaum DR, Zhao Y, Farhi S, Klapoetke NC, Werley CA, Kapoor V, Zou P, Kralj JM, Maclaurin D, Smedemark-Margulies N, Saulnier J, Boulting GL, Cho YK, Melkonian M, Wong GK, Harrison DJ, Murthy V, Sabatini B, Campbell RE, Boyden ES, Cohen AE*
DOI:10.1038/nmeth.3000

Independent optical excitation of distinct neural populations
Nature Methods, 2014
Klapoetke NC, Murata Y, Kim SS, Pulver SR, Birdsey-Benson A, Cho YK, Morimoto TK, Chuong AS, Carpenter EJ, Tian Z, Wang J, Xie Y, Yan Z, Zhang Y, Chow BY, Surek B, Melkonian M, Jayaraman V, Constantine-Paton M, Wong GK, Boyden ES*
DOI:10.1038/nmeth.2836

Cells and cell lysates: A direct approach for engineering antibodies against membrane proteins using yeast surface display
Methods, 2013
Tillotson BJ, Cho YK, Shusta EV*
DOI:10.1016/j.ymeth.2012.03.010

Antibody library screens using detergent-solubilized mammalian cell lysates as antigen sources
Protein Engineering Design and Selection, 2010
Cho YK, Shusta EV*
DOI:10.1093/protein/gzq029

Development of GFP-based biosensors possessing the binding properties of antibodies
Proc Natl Acad Sci U S A, 2009
Pavoor TV, Cho YK, Shusta EV*
DOI:10.1073/pnas.0902828106

A yeast display immunoprecipitation method for efficient isolation and characterization of antigens
Journal of Immunological Methods, 2009
Cho YK, Chen I, Wei X, Li L, Shusta EV*
DOI:10.1016/j.jim.2008.11.005

A decade of yeast surface display technology: where are we now?
Combinatorial Chemistry and High Throughput Screening, 2008
Pepper LR, Cho YK, Boder ET, Shusta EV*
DOI:PMC2681324

Mining a yeast library for brain endothelial cell-binding antibodies
Nature Methods, 2007
Wang XX, Cho YK, Shusta EV*
DOI:10.1038/nmeth993

shopify analytics ecommerce