About Us

Applying protein engineering to combat neurodegenerative diseases

We aim to develop novel biotherapeutics and biomarkers by studying how proteins cause toxicity and coming up with strategies to prevent it.

More about our research

News

June 2025 - Yu Jeong and Alice joined the group as undergraduate researchers. Welcome!

December 2024 - Erik won the AIChE Division 15 Graduate Student Oral Presentation Award. Congrats!

November 2024 - Emily Molino joined the group as a PhD student. Welcome!

August 2024 - Ai Han joined the group as a PhD student. Welcome!

August 2024 - Monika's protocol on yeast biopanning was published in Star Protocols.

July 2024 - Our group received the Tauopathy Challenge Grant from the Rainwater Charitable Foundation. We thank the support from the foundation to study the role of tau protein in primary tauopathies.

 

May 2024 - Azeem joined the group as a PhD student. Welcome!

March 2024 - Fatemeh joined the group as a PhD student. Welcome!

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Highlights

Protocol for screening and validating antibodies specific to protein phosphorylation sites using a set of yeast biopanning approaches (Star Protocols, 2024)

Yeast biopanning against site-specific phosphorylations in tau (Protein Engineering Design & Selection, 2023)

Targeted degradation of microtubule-associated protein tau using an engineered nanobody-E3 ubiquitin ligase adapter fusion (bioRxiv, 2022)

Degradation-driven protein level oscillation in the yeast Saccharomyces cerevisiae (Biosystems, 2022)