About Us

Applying protein engineering to combat neurodegenerative diseases

We aim to develop novel biotherapeutics and biomarkers by studying how proteins cause toxicity and coming up with strategies to prevent it.

More about our research

News

November 2024 - Emily Molino joined the group as a PhD student. Welcome!

August 2024 - Ai Han joined the group as a PhD student. Welcome!

August 2024 - Monika's protocol on yeast biopanning was published in Star Protocols.

May 2024 - Azeem joined the group as a PhD student. Welcome!

March 2024 - Fatemeh joined the group as a PhD student. Welcome!

October 2023 - Cristian joined the group as a full-time research specialist. Welcome!

September 2023 - Katelynn and Youn joined the lab as undergraduate researchers. Welcome!

June 2023 - Monika's paper Yeast biopanning against site-specific phosphorylations in tau was published in Protein Engineering Design and Selection.

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Highlights

Protocol for screening and validating antibodies specific to protein phosphorylation sites using a set of yeast biopanning approaches (Star Protocols, 2024)

Yeast biopanning against site-specific phosphorylations in tau (Protein Engineering Design & Selection, 2023)

Targeted degradation of microtubule-associated protein tau using an engineered nanobody-E3 ubiquitin ligase adapter fusion (bioRxiv, 2022)

Degradation-driven protein level oscillation in the yeast Saccharomyces cerevisiae (Biosystems, 2022)